Software Developer (Front-End, Gwas Catalog)

European Bioinformatics Institute (Embl-Ebi) | Hinxton

Date listed

2 weeks ago

Employment Type

Full time

Glassdoor Rating

4/5 (59 reviews)

The Samples, Phenotypes and Ontologies team is part of the Molecular Archives Cluster and shares projects such as the GWAS (Genome-Wide Association Study) Catalog with the Genes, Genomes and Variation Cluster. We also collaborate closely with EMBl-EBI colleagues.

The GWAS Catalog is a manually curated, high-quality repository of all published genome-wide association studies and has been running since 2008. It is considered the “go-to” resource for looking up findings relating human genotype to phenotype associations. GWAS studies give scientists insight into the association between small variations in the human genome, and biological traits, phenotypes or diseases. The GWAS Catalog is responsible for collecting these data and making them Findable, Accessible, Interoperable and Reusable (FAIR) so they can be served back to the community for analysis and discovery.  We’re looking for an experienced software developer to join the GWAS Catalog development team and help take our infrastructure to the next level.  You’ll be working on the full software stack, taking ownership of the GWAS Catalog interfaces with the opportunity to influence the design and development of the system to meet future challenges in this exciting era of genomic science.

You should be a strong Java programmer who is excited and interested in complex data integration and presentation problems. You should be excited about front-end technologies and frameworks as well as working closely with other developers to find new and efficient ways to create tools for summarising and visualising complex data.

You will also need to be capable of working with non-technical biologists to maintain a strong focus on the biological requirements of the GWAS Catalog, and ideally have familiarity with conducting user experience testing to ensure that the Catalog is tailored to our users’ requirements.

Your role

The position is a fantastic opportunity to gain hands-on experience at working on a project with major scientific impact in a world-leading bioinformatics institute.

You’ll be part of a multi-disciplinary team that is using modern JavaScript technologies with Solr, Neo4j, Java and Spring framework to query and process semantically annotated big data. The project presents interesting challenges for the presentation of complex biological data to users in an intuitive, and visually appealing way. You will have the exciting opportunity to design and develop new interfaces, integrating a range of new search and query features that focus on genome wide association studies data. You have an eye for design, visual aesthetics and extraordinary attention to detail.

You'll be leveraging design patterns to create simple and reusable components for complex user interfaces by writing clean, maintainable, and reusable cross-browser codes. You’ll also be working with existing interfaces to develop new web-based tools including cluster diagrams, heatmaps, network projections as well as integrating existing tools from other resources.

Key elements of the role include:
  • Developing and maintaining NHGRI-EBI GWAS Catalog software using a combination of technologies;
  • Developing new applications to complement and replace the existing NHGRI-EBI GWAS Catalog infrastructure, such as developing a new curation interface Liaising with users to gather requirements and translating these into technical specifications and test plans;
  • Work as part of a team that follows the Agile model of software development involving sprints in which user requirements are prioritised via issue tracking software;
  • Configure and deploy software using version control and continuous integration tools;
  • Investigating new technologies which could be utilised in NHGRI-EBI GWAS Catalog development and within the wider SPOT team;
  • Representing the SPOT/NHGRI-EBI GWAS team at meetings and conferences of both a biological and technical nature held with collaborators and by external organisations;
  • Understand the role of ontologies and semantic web technologies in order to develop applications capable of semantically enriching the raw GWAS data by annotation to ontologies—prior experience of working with ontologies or semantic web technologies would be desirable.

You have

You should be a strong Java programmer who is excited and interested in complex data integration and presentation problems. You should be excited about front-end technologies and frameworks as well as working closely with other developers to find new and efficient ways to create tools for summarising and visualising complex data. You will also need to be capable of working with non-technical biologists to maintain a strong focus on the biological requirements of the GWAS Catalog, and ideally have familiarity with conducting user experience testing to ensure that the Catalog is tailored to our users’ requirements.  If you have a biological background, or have worked in a bioinformatics environment in the past, you’ll have a distinct advantage but training in this area will be provided if required. 

Essential Skills
  • Degree in either Computer Science or Bioinformatics;
  • 2 years’ experience developing software and contributing to a production system or service;
  • A good understanding of all aspects of full stack development, including Java (Ideally 8+), JavaEE, Spring boot, SQL, Web MVC, HTML5, CSS, Thymeleaf, ES6 and modern javascript frameworks (React, Angular, TypeScript);
  • Experience in developing clean UI using responsive, front-end frameworks such as Bootstrap and Foundation framework;
  • Experience with RESTful APIs and Graph QL APIs;
  • Proven track record of user interface design and development;
  • Experience in optimizing web applications for maximum speed and scalability;
  • Experience of containerisation with Docker and deployment in Kubernetes on different cloud environments;
  • Experience of software development processes and be comfortable using Git-like workflows and Continuous Integration/Deployment (CI/CD) strategies;
  • Previous experience with NoSQL databases such as MongoDB, Neo4j, Solr, or Elastic search. 
  • Experience in working in agile teams, or be keen to learn.

You might also have

  • Prior experience of working with ontologies or semantic web technology;
  • If you have a biological background, or have worked in a bioinformatics environment in the past, you’ll have a distinct advantage but training in this area will be provided if required. 

Why join us

Our supportive culture encourages personal and professional development and we are committed to ensuring our employees feel valued, supported and empowered to reach their potential at work.